Gastric Cancer Modeling
The CISNET Gastric Working Group, funded as an Incubator Program cancer site, consists of three modeling groups and a coordinating center. Gastric cancer is the fifth most common cancer and the third leading cause of cancer death globally. In the U.S., there are stark disparities in gastric cancer incidence and mortality with many vulnerable minority communities bearing much of thes disease burden. The investigators are focused on performing comparative modeling to provide critical evidence to improve the prevention and early detection of gastric cancer and cancer control policy. The specific aims are:
- Develop gastric cancer simulation models to estimate gastric cancer outcomes for subgroups by race and ethnicity in the U.S.
- Assess the impact of risk factor trends and primary prevention strategies on gastric cancer disparities.
- Evaluate targeted secondary prevention strategies for reducing early onset-related mortality and gastric cancer disparities.
- Adapt the models to evaluate gastric cancer prevention policies in the global setting.